Resistance Training to Improve Fatigue and Physical Function in Postmenopausal Breast Cancer Survivors

Completed · Not applicable

Conditions studied: Cancer

In brief

This study will begin to fill a knowledge gap by determine whether changes in kynurenine metabolism occur following Resistance Training (RT) and relate to reductions in inflammation and improved behavioral and physical function as this may identify potential targets for interventions to promote cancer recovery.

Key facts

Study ID

NCT03539835

Run by

Emory University

People needed

28

Starts

2018-12-10

Expected to finish

2020-03-12

Last updated by the study team

2020-07-27

Who can join

Age: 50 and older, up to 75. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• within 6 months to 10 years post active breast cancer therapy (i.e. surgery/chemotherapy) for stage I-III invasive breast cancer,
• at least 6 months post breast reconstruction (if applicable),
• lack of menses for at least one year,
• BMI 20-35 kg/m2,
• fatigued (subjective reporting ≥3 on a 1-10 scale),
• untrained with regard to structured resistance training (no more than 3x/week).

You may not qualify if…

• plans for surgery (e.g., breast reconstruction) during the study period,
• taking an anticoagulant medication (i.e. heparin, apixaban, rivaroxaban),
• allergic to lidocaine,
• orthopedic or chronic pain condition restricting exercise,
• Mini-Mental Status Examination (MMSE) scores below education-specific cut-points (less than 23 for more than 9th grade education and less than 17 for less than 8th grade education),
• unable to receive physician medical clearance.

Where it is running

• Winship Cancer Institute — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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