Project Remission: Maximizing Outcomes With Intensive Treatments for Combat-Related PTSD
Completed · Not applicable
Conditions studied: Posttraumatic Stress Disorder (PTSD)
In brief
The study compares two intensive outpatient behavioral programs (Massed Prolonged Exposure versus Intensive Outpatient Prolonged Exposure) for the treatment of posttraumatic stress disorder (PTSD) in post-9/11 active duty service members and veterans. The researchers hope to learn if these programs improve treatment outcomes. The researchers predict that Intensive Outpatient Prolonged Exposure (IOP-PE) will be better at treating PTSD than Massed-Prolonged Exposure (Massed PE).
Key facts
- Study ID
- NCT03529435
- Run by
- The University of Texas Health Science Center at San Antonio
- People needed
- 234
- Starts
- 2017-01-27
- Expected to finish
- 2021-05-01
- Last updated by the study team
- 2022-08-08
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Active duty military service member or veteran (age 18- 65 years) who deployed in support of combat operations post-9/11 seeking behavioral health treatment for PTSD.
- PTSD diagnosis as assessed by Clinician-Administered Posttraumatic Stress Scale (CAPS-5).
- Able to speak and read English (due to standardization of outcome measures)
You may not qualify if…
- Current manic episode or a psychotic symptoms requiring immediate stabilization or hospitalization (as determined by the bipolar and psychosis modules of the MINI).
- Current and severe alcohol use warranting immediate intervention based on clinical judgment.
- Evidence of a moderate or severe traumatic brain injury (as determined by the inability to comprehend the baseline screening questionnaires).
- Current suicidal ideation severe enough to warrant immediate attention (as determined by the Depressive Symptoms Index-Suicidality Subscale and corroborated by a clinical risk assessment by a credentialed provider)
- Other psychiatric disorders severe enough to warrant designation as the primary disorder as determined by clinician judgment.
Where it is running
- Carl R. Darnall Army Medical Center — Fort Hood, Texas, United States
- South Texas Veterans Health Care System — San Antonio, Texas, United States
- Brooke Army Medical Center — San Antonio, Texas, United States
- Central Texas Veterans Health Care System — Waco, Texas, United States
Full record on ClinicalTrials.gov
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