Habitual Diet and Avocado Trial
Completed · Not applicable
Conditions studied: Intra-abdominal Fat, Metabolic Syndrome, High Cholesterol, Triglycerides High, Diet Habit, High Blood Sugar, Liver Fat, Dietary Modification, HDL Cholesterol, Low Serum, Cardiovascular Diseases, High Density Lipoprotein Deficiency, Low-density-lipoprotein-type, Cardiovascular Risk Factor, Diabetes
In brief
The Habitual Diet and Avocado Trial will evaluate the effects of providing one avocado per day for recommended consumption over a 6 month period in a cohort of approximately 1000 free-living participants with increased waist circumference in comparison with a control group that will maintain their habitual diets. Participants will be recruited and screened at 4 clinics in 4 locations: Pennsylvania State University; Loma Linda University; UCLA, and Tufts University (250 per site).
Key facts
- Study ID
- NCT03528031
- Run by
- Wake Forest University Health Sciences
- People needed
- 1008
- Starts
- 2018-06-19
- Expected to finish
- 2020-10-30
- Last updated by the study team
- 2023-03-22
Who can join
Age: 25 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Increased waist circumference defined as ≥35 inches for women, ≥40 inches for men
- At least 25 years old at screening
- Not currently eating more than 2 avocados per month (habitual intake in U.S.)
You may not qualify if…
- Does not eat avocados
- Sensitive / allergic to avocados
- Allergies to latex or oral allergy syndrome
- Not willing or unable to undergo MRI scans
- Unstable medical condition such as on dialysis for renal disease, cardiac, gastrointestinal, or hepatic disease, cancer (non-melanoma skin cancer >5 years ago acceptable, any cancer site >10yrs without recurrence).
- Pregnant, lactating, intention of pregnancy
- Lost or gained 10 lbs of body weight in last year
- Following restricted or weight loss dietary patterns
- Unstable anti-anxiety / anti-depressive / anti-psychotic medication use defined as dose change within last 6 months
- Oral steroid use within the last 6 months longer than 7 days
- Elevated alcohol intake (7+ drinks/week females; 14+ drinks/week males)
- Participation in another clinical intervention trial within 30 days of baseline
- PI judgment
Where it is running
- Loma Linda University — Loma Linda, California, United States
- University of California Los Angles (UCLA) — Los Angeles, California, United States
- Tufts University — Boston, Massachusetts, United States
- Pennysylvania State University — University Park, Pennsylvania, United States
Full record on ClinicalTrials.gov
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