Effect of Late Dinner on Nocturnal Metabolism

Completed · Not applicable

Conditions studied: Healthy

In brief

This study examines the impact of routine dinner time versus late dinner time on nocturnal metabolism. Specifically, investigators will examine plasma profiles of free fatty acids, glucose, insulin, triglycerides, and oxidation of dietary fat.

Key facts

Study ID

NCT03525717

Run by

Johns Hopkins University

People needed

34

Starts

2018-05-08

Expected to finish

2020-01-01

Last updated by the study team

2020-12-02

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy male and female adult volunteers, age 18-30.
• Accustomed to a bedtime between 10:00 PM and 1:00 AM.

You may not qualify if…

• Sleep disorder including insomnia, sleep apnea, circadian rhythm disorder, restless leg syndrome, narcolepsy, shift work sleep disorder
• Gastroesophageal reflux disease that affects ability to tolerate a dinner close to bed time.
• Chronic use of sedative hypnotics, anxiolytics, opiates
• Use of medications that can affect circadian rhythm (beta blockers, melatonin)
• Active smoking (may interfere with metabolism and CRU activities)
• Diabetes (type 1 or 2)
• Obesity (BMI≥30)
• Pregnant or lactating female (pregnancy test will be required)
• Professional or collegiate athlete

Where it is running

• Johns Hopkins Bayview Medical Center — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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