A Study of VX-445 Combination Therapy in CF Subjects Homozygous for F508del (F/F)

Completed · Phase 3 · Has a placebo group

Conditions studied: Cystic Fibrosis

In brief

This study will evaluate the efficacy of VX-445 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are homozygous for the F508del mutation (F/F)

Key facts

Study ID
NCT03525548
Run by
Vertex Pharmaceuticals Incorporated
People needed
113
Starts
2018-08-03
Expected to finish
2018-12-28
Last updated by the study team
2020-01-27

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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