Semantic and Syntactic Computerized Analysis of Free Speech

Recruiting now

Conditions studied: Psychotic Disorders, Psychosis, Schizophrenia and Related Disorders, Schizophrenia Prodromal, Diagnosis, Psychiatric

In brief

Subtle speech disorganization could be predictive of a transition to schizophrenia of ultra-high-risk patients. The aim of our longitudinal multicenter cohort study is to identify specific linguistic markers of the psychotic transition to validate a french predictive model of this transition using computerized speech analysis techniques

Key facts

Study ID

NCT03525054

Run by

University Hospital, Brest

People needed

215

Starts

2018-05-18

Expected to finish

2030-05-02

Last updated by the study team

2026-06-02

Who can join

Age: 15 and older, up to 30. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Major and/or minor from 15 to 30 years old
• Who alleged a suicidal gesture or idea or behavior that has repercussions in their emotional, social or professional life
• If patients receive neuroleptic treatment that impairs cognitive abilities, a one-week wash-out period will be scheduled prior to assessment.
• Affiliated with or beneficiary of a health insurance/social security system
• Able and willing to provide written informed consent

You may not qualify if…

• History of psychosis
• Risk of self-harm or violence not compatible with outpatient treatment
• QI<70 (WAIS)
• Neurological disorder or major health problem
• Impossibility to interrupt neuroleptic treatment for one week
• Refusal to participate

Where it is running

• CHRU de Brest — Brest, France (enrolling)
• CH de SAINT ANNE — Paris, France (enrolling)
• Meunier Sophie — Caen, France

Full record on ClinicalTrials.gov

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