Pre-emptive Analgesics in Orthodontic Treatment

Completed · Phase 4

Conditions studied: NSAID, Pain Management

In brief

This study is designed to determine if the preemptive use of a combination of acetaminophen and ibuprofen is more effective in reducing pain following orthodontic tooth movement when compared to the use of acetaminophen and ibuprofen alone.

Key facts

Study ID

NCT03523988

Run by

University of Washington

People needed

73

Starts

2017-05-02

Expected to finish

2017-08-01

Last updated by the study team

2019-08-21

Who can join

Age: 12 and older, up to 59. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Orthodontic patient presenting for orthodontic treatment

You may not qualify if…

• History of taking an analgesic in the past six hours
• Hypersensitivity to ibuprofen or acetaminophen
• Aspirin-sensitive asthma
• Renal or liver impairment
• History of GI bleeding or ulcers
• Cardiovascular disease, recent myocardial infarction, heart failure, or coronary artery bypass graft surgery
• Currently taking antibiotics or other medications for a chronic systemic disease
• Bleeding disorder
• Pregnant or nursing

Where it is running

• University of Washington — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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