Exercise Intervention After Cancer Treatment for Improving Health in Stage II-III Breast Cancer Survivors

Completed · Not applicable

Conditions studied: Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Cancer Survivor, Estrogen Receptor Positive, HER2/Neu Negative, Progesterone Receptor Positive, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8, Sedentary Lifestyle

In brief

This pilot trial studies how well exercise intervention after cancer treatment works in improving physical activity in stage II-III breast cancer survivors. An exercise intervention may promote regular physical activity.

Key facts

Study ID

NCT03523195

Run by

Fred Hutchinson Cancer Center

People needed

20

Starts

2018-04-18

Expected to finish

2019-07-15

Last updated by the study team

2019-07-22

Who can join

Age: 19 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Single malignancy with diagnosis of breast cancer diagnosis of stage II-III, estrogen and progesterone positive, HER-2neu negative, and on stable dose of aromatase inhibitor (AI) for past 3 months, with AI expected to be stable for the study duration
• No evidence of disease
• 1-5 years post active treatment for malignancy
• Body mass index 19 to 35
• Sedentary (< 100 minutes of moderate intensity exercise per week)
• English adequate to complete assessments and follow exercise instructions
• Able to independently use transportation to attend 2-day a week onsite exercise training
• Access to a computer or smartphone

You may not qualify if…

• Current tobacco use or electronic cigarette smoker
• Pregnant
• Diabetes requiring insulin injection
• Lymphedema that restricts range of motion or with worsening symptoms in the past month, or without compression garment
• Weight change of more than 10 pounds in previous 3 months will exclude from study participation at baseline
• Medical or other issue impacting exercise ability or safety, or ability to comply with study procedures (e.g. significant vision or cognitive impairment, major illness, in hospital or other institution), and specifically:
• Have been hospitalized within 3 months prior to screening for major atherosclerotic events (e.g. myocardial infarction, target-vessel revascularization, coronary bypass surgery, stroke or blood clot) or other major medical condition (as determined by an investigator) that may put the subject at risk because of his/her participation in the study;
• Have an implanted cardiac pacemaker or other implanted cardiac device;
• Have chronic, uncontrolled hypertension as judged by the investigator;
• Have a creatinine clearance < 45 mL/min as calculated by the Cockcroft-Gault equation;
• Subject's hand or legs have mobility impairment from fractures, arthritis, surgery, muscle disease or other injury that may interfere with any study procedure or ability to exercise

Where it is running

• Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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