Myocardial Injury and Intraoperative Tissue Oximetry in Patients Undergoing Spine Surgery

Completed

Conditions studied: Hypoxia, Myocardial Injury, Surgery--Complications

In brief

Myocardial injury after non-cardiac surgery (MINS) is common in patients undergoing major surgery. Many of the events are undetected and associated with a high 30-day mortality risk. Knowledge of which perioperative factors that predicts MINS is lacking. Decrease in tissue oxygenation (StO2) is common in patients undergoing major spine surgery and is associated with postoperative complications in these patients. However, an association between decrease in tissue oxygenation and MINS has not been examined. This group of patients may have other potential predictors of postoperative complications that the study group would like to investigate. In this observational cohort study, we will include 70 patients undergoing major spine surgery at University of California San Francisco. The primary hypothesis is that decrease in intraoperative tissue oxygenation is associated with postoperative myocardial injury.

Key facts

Study ID

NCT03518372

Run by

University of California, San Francisco

People needed

70

Starts

2018-01-02

Expected to finish

2018-07-24

Last updated by the study team

2020-06-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female ≥18 years
• Patient is undergoing elective surgery of the spine
• Surgery is scheduled to last ≥ 2 hours and involve instrumentation

You may not qualify if…

• Patient is < 18 years
• Patient is undergoing emergent or urgent surgery
• American Society of Anesthesiologist (ASA) status > IV
• Patient is undergoing non-instrumental surgery, such as laminectomy alone
• Patient is undergoing spine surgery for tumor or infection

Where it is running

• UCSF Medical Center — San Francisco, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.