Fecal Microbiota Transplantation for Radiation Enteritis

Recruiting now · Not applicable

Conditions studied: Radiation Enteritis

In brief

Radiation enteritis is one of the most feared complications after abdominal or pelvic radiation therapy.The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body metabolism. Evidence from animal studies demonstrated the link between intestinal bacteria and radiation enteritis. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation (FMT) for radiation enteritis.

Key facts

Study ID

NCT03516461

Run by

The Second Hospital of Nanjing Medical University

People needed

70

Starts

2018-01-07

Expected to finish

2025-07-01

Last updated by the study team

2025-03-30

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age ≥18 years old;
• Radiation enteritis diagnosed by colonoscopy after finishing radiotherapy.

You may not qualify if…

• Patients who were pregnant or nursing;
• Patients who were unable or unwilling to undergo a gastroscopy;
• Patients who had gastrointestinal infection;
• Patients with cardiopulmonary failure.

Where it is running

• Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University — Nanjing, Jiangsu, China (enrolling)

Full record on ClinicalTrials.gov

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