Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults

Completed · Phase 1 · Has a placebo group

Conditions studied: Healthy, Young Adults

In brief

The purpose of this research study is to determine if remote limb ischemic conditioning (RLIC) can enhance learning of a motor (balance) and an ecologically valid, complex cognitive-motor (driving) task, and increase skeletal muscle strength in neurologically-intact young adults.

Key facts

Study ID

NCT03512028

Run by

Washington University School of Medicine

People needed

34

Starts

2017-11-08

Expected to finish

2019-01-31

Last updated by the study team

2020-02-05

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy adults between the age of 18 and 40 years
• Visual acuity of 20/20 with corrected vision

You may not qualify if…

• History of neurological condition (i.e. stroke, Alzheimer's disease, Parkinson's disease), Attention Deficit Hyperactivity Disorder (ADHD), depression, bipolar disorder, balance impairment, or vestibular disorder
• History of severe motion sickness, moderate to severe motion sickness or nausea on oculo-motor components of Simulator sickness questionnaire, inability to ride a car, boat, train or airplane due to motion sickness
• Recent wrist, hand or forearm injury that would currently prevent ability to lift weights
• History of lower extremity condition, injury, or surgery that would currently impair ability to stand or balance
• Any extremity soft tissue, orthopedic, or vascular injury (i.e. peripheral vascular disease) which may contraindicate RLIC
• Any cognitive, sensory, or communication problem that would prevent completion of the study
• History of or current sleep apnea
• Current intensive weight lifting or interval training exercise
• Current substance abuse or dependence
• Unwillingness to travel for all study visits

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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