Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
Stopped early
Conditions studied: Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
In brief
Background: PANS is an illness that comes on suddenly in children. The full name is Pediatric Acute-Onset Neuropsychiatric Syndrome. It can cause sudden obsessive-compulsive behaviors. It can also cause children to suddenly restricte their food intake. Researchers want to learn more about children with PANS. They also want to learn more about the illness. Objective: To study some disorders of behavior and emotion that start in childhood. Eligibility: Children 3 14 years old who have had severe obsessive-compulsive symptoms or food restriction start quickly Design: Parents will answer questions. The topics include: Their child s medical history Their child s physical and mental health Their family history. The focus will be on neurodevelopmental and psychiatric conditions. A family tree will be drawn. Participants will have a physical exam. Participants may take tests on paper or computer. These will focus on thinking, memory, and behavior. Participants and parents will give a blood sample. Participants will have magnetic resonance imaging (MRI). A strong magnetic field and radio waves take pictures of the brain. Participants will lie on a table that slides in and out of a metal scanner. Participants may have photos or videos taken. Participants may have other tests. These may include heart tests, sleep tests, and lumbar puncture. Sponsoring Institute: National Institute of Mental Health
Key facts
- Study ID
- NCT03507218
- Run by
- National Institute of Mental Health (NIMH)
- People needed
- 9
- Starts
- 2018-03-20
- Expected to finish
- 2019-10-23
- Last updated by the study team
- 2019-10-25
Who can join
Age: 3 and older. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Participants will not be eligible if they:
- Appear to the investigators to be too unstable psychiatrically or medically to participate safely in the protocol.
- Are unwilling or unable to be evaluated and followed prospectively.
- Have a parent/guardian who is not willing to participate at a distance through web-based or phone-based data collection.
Where it is running
- University of Arizona — Tucson, Arizona, United States
- Lucille Salter Packer Children's Hospital — Stanford, California, United States
- Nemours/Alfred I. duPont Hospital for Children — Wilmington, Delaware, United States
- University of Southern Florida — Tampa, Florida, United States
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States
- Harvard Medical School — Boston, Massachusetts, United States
- University of Minnesota — Minneapolis, Minnesota, United States
- University of Missouri — Columbia, Missouri, United States
Full record on ClinicalTrials.gov
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