Reducing Risk for Alzheimer's Disease in High-Risk Women Through Yogic Meditation Training

Completed · Not applicable

Conditions studied: Mild Cognitive Impairment, Alzheimer's Disease

In brief

The purpose of this pilot study will be to test whether Kundalini yoga (KY) and Kirtan Kriya (KK) yogic meditation is superior to Memory Enhancement Training (MET) for improving cognitive functioning, health (including cardiovascular factors), and mood in women with high AD risk.

Key facts

Study ID

NCT03503669

Run by

University of California, Los Angeles

People needed

100

Starts

2018-05-01

Expected to finish

2021-02-01

Last updated by the study team

2024-02-08

Who can join

Age: 50 and older, up to 90. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Amnestic MCI, as defined by a Clinical Dementia Rating Scale score of .5.
• High cardiovascular risk defined as at least one of the following:
• 7.5 percentile risk or higher using ASCVD risk calculator
• Myocardial Infarction more than 6 months ago
• Diabetes
• Taking medication for blood pressure > 140/90 blood pressure
• Taking medication for lyperlipidemia LDL >160
• Sufficient English proficiency and the 8th grade or higher reading level as determined by the word reading subtest of the Wide Range Achievement Test-IV (this criterion is necessary in order to ensure ability to participate in MET, which involves reading and writing and has a Flesch-Kinkaid school equivalency of 7th grade)
• Capacity to provide informed consent

You may not qualify if…

• History of psychosis, bipolar disorder, alcohol/ drug dependence, or neurological disorder
• Recent (within three months) surgery, anticipated surgery within next year, or unstable medical condition
• Any disability preventing participation in MET or KK+KY (e.g., severe visual or hearing impairment)
• Insufficient English proficiency to participate in either MET or KK+KY
• Diagnosis of dementia
• Mini Mental Health Examination score of 23 or below
• Currently taking any psychoactive medication
• Participation in a psychotherapy that involves cognitive training
• Practice of Kundalini Yoga or Kirtan Kriya within the past year
• Myocardial Infarction within the past 6 months

Where it is running

• UCLA Semel Institute — Los Angeles, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.