Effects of Nicotinamide Riboside on Metabolism and Vascular Function

Completed · Not applicable · Has a placebo group

Conditions studied: Aging, Lipemia

In brief

The purpose of this study is to determine the effects of Nicotinamide Riboside (NR) supplementation on metabolism and vascular function following high-fat meal. Differences between young (18-35) and older (60-75) adults will be determined.

Key facts

Study ID

NCT03501433

Run by

Iowa State University

People needed

16

Starts

2018-02-01

Expected to finish

2019-12-01

Last updated by the study team

2020-09-25

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18 to 35 (young) and 60 to 75 (older)
• Normo- or pre-hypertensive (blood pressure <140/90 mmHg)
• Non-smokers
• Able to give informed consent and participate in all laboratory visits

You may not qualify if…

• Currently taking any medications that could interfere with cardiovascular or metabolic outcomes will be excluded from the study (e.g., beta-blockers)
• Known metabolic (e.g. Type I or Type II diabetes, cardiovascular disease, etc.) or immunologic (e.g. HIV, cancer, autoimmune, etc.) diseases
• Food allergies to egg, milk, soy or wheat
• Women who are pregnant or planning to become pregnant during the course of the study,
• Pacemaker or other implanted device
• Unwilling to participate in the experimental protocol or blood draws will be excluded

Where it is running

• Iowa State University — Ames, Iowa, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.