Half-normal Saline in Atrial Fibrillation Ablation

Completed · Not applicable

Conditions studied: Atrial Fibrillation

In brief

The study evaluates the use of half-normal saline as an irrigant for open-irrigated catheters during atrial fibrillation ablation. By increasing the efficacy of radiofrequency energy-mediated lesion formation, half-normal saline has the potential to reduce procedural times and improved acute and long-term outcomes.

Key facts

Study ID

NCT03498586

Run by

Texas Cardiac Arrhythmia Research Foundation

People needed

99

Starts

2018-05-02

Expected to finish

2020-05-02

Last updated by the study team

2022-04-05

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• male or female between 18 and 75 years of age at the time of enrollment
• undergoing first-time radiofrequency ablation for atrial fibrillation
• written informed consent obtained from subject or subject's legal representative and ability for subject to comply with the requirements of the study

You may not qualify if…

• robotic-guided atrial fibrillation ablation
• baseline hyponatremia (serum sodium level < 135 mEq/L)
• pregnant, breastfeeding, or unwilling to practice birth control during participation in the study
• presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data

Where it is running

• Texas Cardiac Arrhythmia Institute, St. David's Medical Center — Austin, Texas, United States
• Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada

Full record on ClinicalTrials.gov

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