More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents
Completed · Phase 1/Phase 2
Conditions studied: HIV Infections
In brief
The purpose of this study was to determine the dosage for oral cabotegravir (CAB) and long-acting cabotegravir (CAB LA) and long-acting rilpiverine (RPV LA) and evaluate the safety, acceptability, tolerability, and pharmacokinetics (PK) of oral CAB, CAB LA, and RPV LA in virologically suppressed children and adolescents living with HIV.
Key facts
- Study ID
- NCT03497676
- Run by
- National Institute of Allergy and Infectious Diseases (NIAID)
- People needed
- 168
- Starts
- 2019-04-03
- Expected to finish
- 2025-04-22
- Last updated by the study team
- 2026-01-28
Who can join
Age: 12 and older, up to 17. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Usc La Nichd Crs — Los Angeles, California, United States
- Univ. of Colorado Denver NICHD CRS — Aurora, Colorado, United States
- Pediatric Perinatal HIV NICHD CRS, Site 5127 — Miami, Florida, United States
- Emory University School of Medicine NICHD CRS — Atlanta, Georgia, United States
- Lurie Children's Hospital of Chicago (LCH) CRS — Chicago, Illinois, United States
- Johns Hopkins Univ. Baltimore NICHD CRS — Baltimore, Maryland, United States
- St. Jude Children's Research Hospital CRS — Memphis, Tennessee, United States
- Baylor College of Medicine/ Texas Children's Hospital NICHD CRS — Houston, Texas, United States
- Gaborone CRS — Gaborone, South-East District, Botswana
- Molepolole CRS, Site 12702 — Molepolole, Botswana
- Famcru Crs — Tygerberg Hills, Western Cape, South Africa
- Wits RHI Shandukani Research Centre CRS — Johannesburg, South Africa
- Soweto CRS, Site 8052 — Soweto, South Africa
- Umlazi CRS — Umlazi, South Africa
- Siriraj Hospital Mahidol University — Bangkok, Thailand
- Chiangrai Prachanukroh Hospital NICHD CRS — Chiang Mai, Thailand
- Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS — Chiang Mai, Thailand
- Baylor-Uganda CRS — Kampala, Uganda
- MU-JHU Care Limited CRS — Kampala, Uganda
Full record on ClinicalTrials.gov
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