Impact of Exercise in Parkinson's Disease

Completed · Not applicable

Conditions studied: Parkinson Disease

In brief

The goal of this research is to identify an intervention that will improve cognition and sleep in persons with PD.

Key facts

Study ID

NCT03495193

Run by

University of Alabama at Birmingham

People needed

4

Starts

2017-05-18

Expected to finish

2018-11-30

Last updated by the study team

2019-04-26

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• a clinical diagnosis of idiopathic PD, based on the presence of bradykinesia as well as rest tremor and/or rigidity;
• Hoehn and Yahr stage 2-3;
• age ≥ 45;
• on stable medications for at least 4 weeks prior to study entry;
• Participants must have Montreal Cognitive Assessment (MoCA) score ≥ 18;
• No contraindications to an exercise program, based on the Physical Activity Readiness Questionnaire (PAR-Q), resting physical examination, and 12-lead electrocardiogram.

You may not qualify if…

• features suggestive of atypical Parkinsonism (cerebellar signs, supranuclear gaze palsy, prominent autonomic failure, or prominent upper motor neuron signs);
• secondary Parkinsonism (multiple strokes with stepwise progression of Parkinsonism, neuroleptic treatment at time of diagnosis, or multiple head injuries);
• inability to walk without a cane or walker;
• regular participation in an exercise program in the past 6 months;
• presence of deep brain stimulator; and
• untreated sleep apnea.

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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