Project BIPAMS: Behavioral Intervention for Physical Activity in Multiple Sclerosis

Running, not enrolling · Not applicable

Conditions studied: Multiple Sclerosis

In brief

This randomized controlled trial will examine the effect of a 6-month behavioral intervention, based on social cognitive theory and delivered through the Internet, for increasing physical activity and secondarily improving mobility, cognition, symptoms and quality of life in persons with MS. The investigators hypothesize that individuals who receive the 6-month behavioral intervention will demonstrate an increase in physical activity behavior that will last throughout a 6-month follow up compared with participants in the control condition. The investigators further hypothesize that individuals in the behavioral intervention will demonstrate better walking mobility and cognitive function, reduced fatigue, depression, anxiety, and pain, and improved quality of life compared to the control condition. The investigators hypothesize that the behavioral intervention will increase physical activity through positive changes in self-efficacy, outcome expectations, goal setting, and impediments as social-cognitive determinants.

Key facts

Study ID

NCT03490240

Run by

University of Alabama at Birmingham

People needed

280

Starts

2018-03-01

Expected to finish

2026-12-31

Last updated by the study team

2025-12-22

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of MS
• Relapse free in the past 30 days
• Internet and email access
• Willingness to complete the questionnaires, wear the accelerometer, and undergo randomization
• Being non-active defined as not engaging in regular activity (30 minutes accumulated per day) on more than 2 days of the week during the previous six months
• Ability to ambulate with or without assistance (i.e. walking with or without a can or walker, but not a wheelchair)
• Age between 18 and 64

You may not qualify if…

• Moderate or high risk for undertaking strenuous or maximal exercise per participants response to the PAR-Q. Those who report no more than one YES or affirmative on the 7 item PAR-Q will be considered at low risk and included for participation. All others will be considered at moderate or high risk and excluded from participation.

Where it is running

• Exercise Neuroscience Research Lab — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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