Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery
Withdrawn before enrolling · Phase 2 · Has a placebo group
Conditions studied: Dysphagia, GERD, Degenerative Joint Disease
In brief
The researchers wish to investigate whether proton pump inhibitors, administered prior to or after surgery, can reduce the incidence and/or severity of difficulty swallowing foods and/or liquids,following anterior cervical surgery.
Key facts
- Study ID
- NCT03488147
- Run by
- Icahn School of Medicine at Mount Sinai
- People needed
- 0
- Starts
- 2020-07-01
- Expected to finish
- 2020-07-02
- Last updated by the study team
- 2020-11-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Must be at least 18 years of age.
- Scheduled to undergo anterior cervical surgery for degenerative joint disease.
You may not qualify if…
- Patients undergoing revision procedures, multi-level procedures, or procedures treating conditions other than degenerative joint disease.
- Patients with preoperative dysphagia.
- Patients currently taking any acid suppressing medications (proton pump inhibitors, H2 blockers, antacids, etc).
- Patients who are pregnant or nursing.
- Patients who, due to drug allergies, hypersensitivities/anaphylactic reactions to esomeprazole or contraindications (hypersensitivity to benzimidazoles, osteoporosis), are unable to take esomeprazole.
- Patients unable to attend follow-up visits or answer the dysphagia questionnaires.
- Eligibility Criteria:
- Scheduled to undergo anterior cervical surgery for degenerative joint disease.
Where it is running
- Mount Sinai West — New York, New York, United States
- Icahn School of Medicine at Mount Sinai — New York, New York, United States
Full record on ClinicalTrials.gov
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