Stress, Sleep and Cardiovascular Risk

Status unconfirmed · Not applicable

Conditions studied: Posttraumatic Stress Disorder, Insomnia

In brief

We are evaluating a model where trauma exposure and threatening environments elicit nocturnal vigilance and sleep-related fears that compromise the healthy reduction of autonomic arousal during sleep which in turn stimulates secretion of atherogenic humoral factors, arterial stiffening, and cardiovascular disease risk. We will examine the roles of pre-sleep cognition using a questionnaire and real time assessment, and modifiable strategies for coping with sleep disruptive cognitions. We will then evaluate the impact of providing personalized feedback and recommendations based on study observations on how participants cope with potentially sleep disruptive cognitions and sleep efficiency in a randomized trial.

Key facts

Study ID

NCT03487991

Run by

Howard University

People needed

168

Starts

2017-10-01

Expected to finish

2021-10-31

Last updated by the study team

2018-04-04

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• current medical or psychiatric condition that affects sleep or requires daily - use of medication other than PTSD, phobic disorders, or past history of major depression
• severe alcohol or drug use disorders
• overnight shift worker or an extreme chronotype
• sleep disorder other than insomnia or nightmares
• morbid obesity (body mass index > 40)

Where it is running

• Clinical Research Unit; Howard University Hospital — Washington D.C., District of Columbia, United States (enrolling)

Full record on ClinicalTrials.gov

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