A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It is a Clinical, Radiographic and Histomorphometric Study.
Completed · Not applicable
Conditions studied: Alveolar Ridge Preservation, Tooth Extraction
In brief
This 14 weeks longitudinal study will be conducted from March 2018 to June 2020, with a 40 participants. No subjects has received placebo medication at any point in the research procedures. Null hypothesis: The use of L-PRF plug, in combination with non-resorbable, open barrier membrane technique to fill the extraction sockets will have no effect on the quality of the newly formed bone nor on the dimensional changes of the ridge, compared to non-resorbable, open barrier membrane technique with natural blood clot.
Key facts
- Study ID
- NCT03487718
- Run by
- Firas Al Yafi
- People needed
- 27
- Starts
- 2018-03-26
- Expected to finish
- 2020-06-30
- Last updated by the study team
- 2021-05-24
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- The subject must have an unsalvageable tooth that is planned for extraction and delayed implant placement.
- The tooth should be free of acute odontogenic infections.
- Extraction sockets with minimal to moderate bony defect.
You may not qualify if…
- Any patient who is planned for full mouth extraction.
- Heavy smoker (more than 10 cigarettes a day).
- History of malignancy, chemotherapy, radiation therapy.
- Immunosuppressive disease.
- Uncontrolled systemic disease.
- Any contraindications to surgical procedures.
- Females who are pregnant or breastfeeding.
- For multi-rooted teeth, if the most coronal part of the interradicular septum is less than 5 mm below the crest of the bone.
Where it is running
- Univerisity of Kentucky College of Dentistry — Lexington, Kentucky, United States
Full record on ClinicalTrials.gov
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