Acute Effects of E-Cigarette Aerosol Inhalation

Completed · Early Phase 1

Conditions studied: Endothelial Dysfunction, Biochemical Markers

In brief

This study comprises a portion of a larger study designed to compare results of vascular function in non-smokers to vascular function in healthy smokers chronically exposed to nicotinized electronic cigarette aerosol versus conventional cigarettes.

Key facts

Study ID

NCT03479203

Run by

University of Pennsylvania

People needed

31

Starts

2018-05-22

Expected to finish

2022-08-31

Last updated by the study team

2024-05-08

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI of 18.5 - 30

You may not qualify if…

• Cancer
• HIV
• Mental illness
• Overt cardio- or neurovascular disease (prior heart attack, stroke, transient ischemic attacks)
• Serious arrhythmias
• Bronchospastic disease
• Upper respiratory tract infection within the past six weeks
• Chronic medication or antibiotics
• Claustrophobia / contraindications for MRI

Where it is running

• University of Pennsylvania Perelman School of Medicine — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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