Developing Non-Communicable Disease Registries in Africa : A Step Towards Providing Quality Data for Improving Patient Outcomes

Running, not enrolling

Conditions studied: Non-Communicable Disease

In brief

This umbrella protocol seeks to develop robust data registries for non-communicable diseases (NCDs) in sub-Saharan Africa (SSA) with the aim of providing accurate and comprehensive data for the evaluation of such diseases in sub-Saharan African countries.Healthy volunteers will be included in the study for comparison. Additionally, the investigators aim to describe the gut microbiome community diversity of a cohort of community dwelling Nigerians and compare with CRC patients in Nigerian and at MSK. We will collect stool for microbiome and metabolomic analysis from community dwelling persons in the catchment area of ARGO facilities in Nigeria while contemporaneously administering an extensive medical and environmental exposure questionnaire.

Key facts

Study ID

NCT03473795

Run by

Memorial Sloan Kettering Cancer Center

People needed

6990

Starts

2018-03-16

Expected to finish

2027-03-01

Last updated by the study team

2026-06-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18 and older.
• Suspected or confirmed diagnosis of a non-communicable disease. OR
• Healthy volunteers/no confirmed diagnosis for comparison.

You may not qualify if…

• Participants unwilling to sign consent.
• Participants under the age of 18

Where it is running

• Memorial Sloan Kettering Cancer Center — New York, New York, United States
• National Hospital of Abuja (Data collection only) — Abuja, Central Business District, Nigeria
• Lagos State University Teaching Hospital — Idi-Araba, Lagos, Nigeria
• Olabisis Onabanjo University Teaching Hospital — Sagamu, Ogun State, Nigeria
• Federal Medical Centre Owo — Owo, Ondo State, Nigeria
• University College Hospital — Ibadan, Oyo State, Nigeria
• Ladoke Akintola University of Technology — Ogbomoso, Oyo State, Nigeria
• University Of Nigeria Teaching Hospital (UNTH) Ituku-Ozalla Enugu — Enugu, Nigeria
• Lagos State University Teaching Hospital — Ikeja, Nigeria
• Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC) — Ile-Ife, Nigeria
• University of Ilorin Teaching Hospitals — Ilorin, Nigeria
• University of Maiduguri Teaching Hospital (Data collection only) — Maiduguri, Nigeria
• Ondo State Trauma and Surgical Centre — Ondo, Nigeria
• Federal Medical Centre Owo — Owo, Nigeria

Full record on ClinicalTrials.gov

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