Effectiveness of Orthokeratology in Myopia Control

Completed · Not applicable

Conditions studied: Myopia

In brief

The high prevalence of myopia - especially in Asian countries - is well documented, as are the sight-threatening complications of high or degenerative myopia. Retinal detachment, glaucoma, vitreal degeneration and focal retinal changes may occur secondary to the progressive axial elongation of the eye with age. Specialty rigid lenses have long been shown to lessen this progression in the pediatric population; orthokeratology (ortho-k) lenses are worn at night and change the corneal topography to correct low to moderate amounts of myopia. Most of the studies on orthokeratology were conducted on Asian children. To the best of the investigators knowledge, no study has been done on African American (AA) children. The investigators' project seeks to investigate the efficacy of ortho-k in slowing axial elongation and myopic progression in AA children compared to that in other races.

Key facts

Study ID

NCT03465748

Run by

Illinois College of Optometry

People needed

45

Starts

2017-05-01

Expected to finish

2021-12-01

Last updated by the study team

2023-09-28

Who can join

Age: 6 and older, up to 13. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• myopia progression more than -1.00D in one year
• myopic prescription between -1.00D and -6.00D in at least one eye with refractive astigmatism <1.50D
• Best corrected VA 20/25 or better
• subjects willing to present to clinic for all necessary follow up care
• willing to be randomized to either group

You may not qualify if…

• non-compliance with treatment protocol
• contraindications for orthok as per company guidelines
• history of refractive surgery
• current gas permeable contact lens wearers

Where it is running

• Illinois Eye Institute — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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