Nitrate Supplementation and Muscle Blood Flow

Completed · Not applicable · Has a placebo group

Conditions studied: Vasodilation, Blood Pressure, Active Hyperemia, Aging

In brief

The main purpose of this study is to evaluate the effects of an acute dose of dietary nitrate in the form of beetroot juice on skeletal muscle blood flow in response to dynamic knee extension exercise in healthy older adults. All subjects will receive active (rich in dietary nitrate) or placebo (devoid of nitrate) supplementation.

Key facts

Study ID

NCT03459027

Run by

University of Iowa

People needed

10

Starts

2017-10-10

Expected to finish

2018-02-08

Last updated by the study team

2019-01-09

Who can join

Age: 60 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy older adults 60-80 years of age

You may not qualify if…

• Hypertension,
• Smoking,
• Heart disease,
• Diabetes,
• Body mass index (BMI) ≥ 30 kg/m2,
• Autonomic disorders and other conditions that may alter blood pressure or vascular function
• Medications that might normally alter blood pressure or vascular function.
• Older women taking hormone replacement therapy medications.

Where it is running

• Medical Education Building — Iowa City, Iowa, United States

Full record on ClinicalTrials.gov

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