Precision Pain Management for Major Abdominal Surgery in Colorectal Surgery

Stopped early · Not applicable

Conditions studied: Colorectal Cancer, Diverticular Disease, Crohn Disease, Ulcerative Colitis

In brief

The primary objectives of this study are to evaluate the potential for preoperative pharmacogenomics (PGx) testing to positively influence postoperative opioid use through visual analog scale (VAS) guided administration of narcotic equivalent and lower pain scores as measured by OBAS in patients undergoing major abdominal surgery.

Key facts

Study ID

NCT03455751

Run by

The Cleveland Clinic

People needed

10

Starts

2018-04-17

Expected to finish

2019-01-09

Last updated by the study team

2019-03-18

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subject capable of giving consent
• Age 18-80
• Scheduled for open colorectal resection at Cleveland Clinic main campus (with preoperative appointment scheduled at least five days before date of surgery)

You may not qualify if…

• Patient does not speak English
• Patient with substance-use disorder (including alcohol)
• Patient diagnosed with major depression
• Patient currently taking opioids
• Previous long-term opioid use (> 3 months)
• Previous opioid use with a dose of >100 milligram morphine equivalent (MME)
• Patient has pain-related disorder (e.g. fibromyalgia, sympathetic dystrophy, etc.)
• Documented allergy to pain medication

Where it is running

• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.