Effect of Lifitegrast on Dry Eye Disease Signs and Symptoms

Completed · Phase 4

Conditions studied: Dry Eye

In brief

To determine whether a fall in tear osmolarity precedes improvement in symptoms and signs of dry eye in dry eye patients treated topically with 5% lifitegrast drops for 3 months.

Key facts

Study ID

NCT03451396

Run by

Lifelong Vision Foundation

People needed

30

Starts

2016-12-12

Expected to finish

2018-03-15

Last updated by the study team

2018-03-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Tear Osmolarity > 320 mOsm/L
• VAS eye dryness > 40
• No other ocular pathology
• No contact lens wear
• Not currently on T cell modulator
• No change in therapy in last 2 months
• Willingness to adhere to therapy and study visits
• Patients qualified for prescription of lifitegrast drops

You may not qualify if…

• Contact lens use
• Eye surgery in Past 6 months
• Use of tear supplements in past 2 hours

Where it is running

• Lifelong Vision Foundation — Chesterfield, Missouri, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.