Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates

Recruiting now · Not applicable

Conditions studied: Vasovagal Syncope

In brief

The investigators will seek to determine the effects of different heart rates on both stroke volume and cardiac output using non-invasive hemodynamic assessments. In order to safely manipulate the HR, the investigators will study patients with permanent pacemakers in whom heart rate manipulation can be done in a safe and non-invasive manner.

Key facts

Study ID

NCT03446326

Run by

University of Calgary

People needed

25

Starts

2018-01-01

Expected to finish

2028-01-01

Last updated by the study team

2026-05-05

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-70 years (inclusive)
• Implanted permanent pacemaker or implanted defibrillator capable of atrial and ventricular pacing
• LV ejection fraction >50%

You may not qualify if…

• Unable or unwilling to provide informed consent
• Clinical need for a cardiac resynchronization device

Where it is running

• University of Calgary — Calgary, Alberta, Canada (enrolling)

Full record on ClinicalTrials.gov

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