The Absorption of Bioactive Berberine in Human

Completed · Not applicable

Conditions studied: Healthy

In brief

Berberine from medicinal plants has therapeutic activities against multiple chronic diseases. But its absorption rate is very low. The objective of this study is to test if adding TPGS or Quillaja extract as an emulsifier enhance the absorption of berberine in human.

Key facts

Study ID

NCT03438292

Run by

University of Florida

People needed

32

Starts

2018-09-25

Expected to finish

2020-09-11

Last updated by the study team

2021-01-27

Who can join

Age: 21 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy
• Normal BMI (20-27)

You may not qualify if…

• Pregnancy
• Gastro-intestinal conditions
• Diabetics,
• Alcohol and substance abuse history,
• Allergy to berberine,
• Current berberine use,
• Use of H2 blockers, proton pump inhibitors, blood sugar-lowering agents, or statins

Where it is running

• Food Science and human nutrition department at University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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