Effects of Vitamin B12 Treatment in Singers

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Vitamin B 12 Deficiency

In brief

In this study, the investigators aim to assess if vitamin B12 treatment demonstrates a beneficial effect on voice performance. If so, they wish to examine the relationship between the vitamin B12 treatment and the study participant's general well-being.

Key facts

Study ID

NCT03437824

Run by

University of Southern California

People needed

20

Starts

2017-10-01

Expected to finish

2019-04-01

Last updated by the study team

2019-04-09

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged 18 to 65 years old
• An active singer who is presently singing
• Willing and able to comply with the study requirements
• Completed and signed an informed consent form.

You may not qualify if…

• Known vitamin B12 deficiency
• Active or recent vitamin B12 treatment (the subject must not receive vitamin B12 treatment for at least 4 weeks)
• Any known bleeding disorder
• Any known laryngeal pathology
• Plans to start any new treatment, oral/parenteral anticoagulant, supplement, or medication during the study period
• Scored above the highest 10 percentile of performance in all three voice evaluation questionnaires will be withdrawn from the study before the first injection (i.e., scored less than or equal to 7 in the Voice Fatigue Index (VFI), less than or equal to 6 in the Evaluation of the Ability to Sing Easily (EASE), and less than or equal to 4 in the Singing Voice Handicap Index 10 (SVHI-10))

Where it is running

• Keck Medicine of USC - Downtown Los Angeles — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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