Alternation in the Human Microbiome With Commonly Used Topical Medications

Recruiting now · Phase 1

Conditions studied: Healthy

In brief

The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the human microbiome with short-term use.

Key facts

Study ID
NCT03437005
Run by
University of California, Davis
People needed
24
Starts
2013-01-28
Expected to finish
2026-09-28
Last updated by the study team
2026-02-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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