Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

Recruiting now

Conditions studied: Anesthesia, Intravenous Fluid, Blood Pressure

In brief

In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration. It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.

Key facts

Study ID

NCT03431064

Run by

Boston Children's Hospital

People needed

48

Starts

2018-06-21

Expected to finish

2027-12-31

Last updated by the study team

2025-11-12

Who can join

Age: any, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 0 to < 18 years old
• Undergoing surgery at Boston Children's Hospital under general anesthesia
• mechanically ventilated with an endotracheal tube
• Monitored with an indwelling radial arterial catheter as part of the anesthetic plan for the scheduled surgical procedure

You may not qualify if…

• Prematurity
• Low birth weight
• Congenital heart disease
• Left or right ventricular dysfunction
• Cardiac arrhythmia
• Pulmonary hypertension
• Preoperative parenchymal or interstitial lung disease
• Intracranial hypertension
• Poor transthoracic acoustic window
• Obesity
• Allergy to ultrasound transmission gel
• Need for single lung ventilation
• Systemic hypertension on antihypertensive medications

Where it is running

• Boston Children's Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.