A Phase 3 Efficacy and Safety Study of Intra-articular CNTX-4975-05 (Capsaicin) vs Placebo in Subjects With OA Knee Pain
Completed · Phase 3 · Has a placebo group
Conditions studied: Osteoarthritis, Knee
In brief
This is a phase 3, randomized, double-blind, placebo-controlled, single injection, 52-week study to evaluate the analgesic efficacy and safety of a single intra-articular (IA) CNTX-4975-05 (capsaicin), compared to IA placebo, in subjects with chronic, moderate-to-severe osteoarthritis (OA) knee pain.
Key facts
- Study ID
- NCT03429049
- Run by
- Centrexion Therapeutics
- People needed
- 332
- Starts
- 2018-01-24
- Expected to finish
- 2019-11-22
- Last updated by the study team
- 2022-07-26
Who can join
Age: 40 and older, up to 95. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Alabama Orthopaedic Center - Research — Birmingham, Alabama, United States
- Cahaba Research, Inc — Birmingham, Alabama, United States
- Coastal Clinical Research, Inc — Mobile, Alabama, United States
- Noble Clinical Research, LLC — Tucson, Arizona, United States
- Orange County Research Institute — Anaheim, California, United States
- Core Healthcare Group — Cerritos, California, United States
- Biosolutions Clinical Research Center — La Mesa, California, United States
- Providence Clinical Research — North Hollywood, California, United States
- Medical Associates Research Group — San Diego, California, United States
- Encompass Clinical Research — Spring Valley, California, United States
- Tampa Bay Medical Research, Inc — Clearwater, Florida, United States
- Avail Clinical Research, LLC — DeLand, Florida, United States
- M&M Medical Center, Inc — Miami, Florida, United States
- Sensible Healthcare, LLC — Ocoee, Florida, United States
- Jewett Orthopaedic — Orlando, Florida, United States
- Clinical Research of West Florida, Inc. — Tampa, Florida, United States
- Drug Studies America — Marietta, Georgia, United States
- Georgia Institute for Clinical Research, LLC — Marietta, Georgia, United States
- Atlanta Orthopaedic Institute, LLC — Stockbridge, Georgia, United States
- MediSphere Medical Research Center, LLC — Evansville, Indiana, United States
- Mid America PolyClinic — Overland Park, Kansas, United States
- Tufts Medical Center — Boston, Massachusetts, United States
- Tristan Medical Enterprises PC, dba — North Attleboro, Massachusetts, United States
- Medical Research Associates, Inc — Traverse City, Michigan, United States
- Sundance Clinical Research, LLC — St Louis, Missouri, United States
Full record on ClinicalTrials.gov
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