Preventing Lymphedema in Axillary Lymph Node Dissection

Stopped early · Not applicable

Conditions studied: Lymphedema, Breast Cancer, Melanoma

In brief

The researchers are trying to answer if axillary reverse mapping (ARM) with lympho-venous bypass (LVB) in patients undergoing an axillary lymph node dissection reduces the rate and severity of post-operative lymphedema of the arm.

Key facts

Study ID

NCT03428581

Run by

Mayo Clinic

People needed

264

Starts

2018-04-10

Expected to finish

2025-07-11

Last updated by the study team

2026-02-24

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Patients scheduled to undergo an axillary lymph node dissection
• Patients who in the surgeon's judgement are at high risk to convert to an axillary lymph node dissection based intraoperative findings
• English speaking

You may not qualify if…

• Prior ipsilateral axillary lymph node dissection
• Prior ipsilateral axillary radiation
• Patients undergoing sentinel lymph node biopsy only or at low risk of converting to an axillary lymph node dissection in the surgeon's judgement
• Previous treatment for lymphedema of either arm or prescribed prophylactic treatment for lymphedema.
• Pregnant patients cannot participate in the substudy

Where it is running

• Mayo Clinic in Florida — Jacksonville, Florida, United States
• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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