Endodontic Regenerative Procedure for Immature Non-vital Teeth
Withdrawn before enrolling · Not applicable
Conditions studied: Tooth, Nonvital
In brief
In this clinical trial the investigators will evaluate an alternate treatment option, which was developed for teeth with incomplete roots, called Regenerative Endodontic Procedure (REP). This treatment works by harnessing the blood clot formed within the root canal from tissues surrounding the root as a scaffold for stem cells. These cells could help to increase the thickness and length of the root canal walls resulting in root end maturation. Results from the 50 participants who will receive the REP treatment will be compared with findings with historical data.
Key facts
- Study ID
- NCT03425123
- Run by
- Boston University
- People needed
- 0
- Starts
- 2019-06-01
- Expected to finish
- 2023-01-01
- Last updated by the study team
- 2019-05-03
Who can join
Age: 7 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subjects followed prospectively
- 7-18 years old
- salvageable permanent non-vital tooth with immature apex whether anterior or posterior
- receiving dental care at the Henry M. Goldman School of Dentistry Historical controls
- 7-18 year old
- salvageable permanent non-vital tooth with immature apex whether anterior or posterior
- received care and has accessible records at the Henry M. Goldman School of Dentistry
- had either the Calcium hydroxide apexification or MTA apexification between 2007 and 2017
You may not qualify if…
- allergic to medications necessary to complete procedure
- health status not in: a) ASA-1 no organic pathology or patients in whom the pathological process is localized and does not cause any systemic disturbance or abnormality; nor b) ASA 2 A moderate but definite systemic disturbance, caused either by the condition that is to be treated or surgical intervention or which is caused by other existing pathological processes
- history of dental trauma within 6 months due to possibility of internal and external root resorption.
- if tooth pulp space is needed for post/core final restoration
- pregnancy in female subjects
Where it is running
- Henry M Goldman School of Dental Medicine — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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