Evaluating the Use of Prednisone to Decrease Pegylated Interferon Beta-1a Side Effects

Status unconfirmed · Phase 4

Conditions studied: Multiple Sclerosis

In brief

Some of the most common side effects of the multiple sclerosis drug Plegridy (pegylated interferon beta-1a) include flu-like symptoms and injection site reactions. Physicians often advise patients to take Tylenol or aspirin prior to injection, but in this study the investigators evaluated whether using a low dose of oral steroid in combination with Tylenol reduced flu-like symptoms and injection site reactions.

Key facts

Study ID

NCT03424733

Run by

Holy Name Medical Center, Inc.

People needed

50

Starts

2017-09-25

Expected to finish

2020-05-31

Last updated by the study team

2019-08-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• diagnosed any form of MS (relapsing remitting, primary progressive, secondary progressive), any EDSS (expanded stability status scale) score

You may not qualify if…

• prior allergic reaction to interferon products, congestive heart failure, elevated liver enzymes

Where it is running

• Holy Name Medical Center — Teaneck, New Jersey, United States (enrolling)

Full record on ClinicalTrials.gov

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