Assessment of the Quality and Quantity of Bone Regeneration
Completed · Not applicable
Conditions studied: Bone Quality and Quantity
In brief
The purpose of this study is to histologically and radiographically evaluate the maxillary sinus bone volume and density, with reference to percentage of vital bone present, after four months of grafting with either Osteocel or a cortical-cancellous allograft. 1. To assess the quality and quantity of the maxillary sinus bone prior to the placement of dental implants and subsequent restorations, approximately 20 patients will be randomly assigned to receive an augmentation of the maxillary sinus region using either Osteocel or a cortical-cancellous allograft. 2. With the use of pre-operative and four months post-operative CBCT radiography, the maxillary sinus bone density will be assessed and compared between the individuals receiving Osteocel and the individuals receiving conventional cortical-cancellous allograft material. 3. Histomorphometric analysis will be used to assess, compare and contrast the quality and the quantity of the new vital bone cells generated when using these different graft materials
Key facts
- Study ID
- NCT03417375
- Run by
- Ahmad Kutkut
- People needed
- 11
- Starts
- 2017-11-17
- Expected to finish
- 2018-12-12
- Last updated by the study team
- 2020-10-14
Who can join
Age: 22 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Must be 22 years old or older. Must have at least one edentulous posterior site requiring grafting. Must have an implant restoration to replace at least one tooth in the edentulous site.
- Must be available for the follow-up examinations.
You may not qualify if…
- Current smokers Dental infections of bone Untreated periodontal disease Pregnant patients or those who are nursing Uncontrolled diabetes (via patient reported A1C) Chemotherapy/Radiation patients Autoimmune diseases Kidney disease Liver disease
Where it is running
- University of Kentucky College of Dentistry — Lexington, Kentucky, United States
Full record on ClinicalTrials.gov
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