Frailty in Older HIV-infected Individuals

Recruiting now

Conditions studied: HIV Infections

In brief

Frailty has been proposed as a measure of biological (as opposed to chronological) aging. In this study the investigators plan to: (1) measure frailty in a cohort of older HIV-infected individuals in Hong Kong, and its association with mortality and quality of life; (2) identify risk factors predictive of development of frailty in HIV-infected individuals in Hong Kong; and (3) determine the outcomes of HIV-infected individuals in Hong Kong with and without frailty. The following assessment will be done: 1. Physical examination including measuring height, weight, hip and waist circumference. 2. Grip strength, chair stand test, gait speed test, balance tests, and neurocognitive tests 3. Geriatric syndromes, screening for depression, disability and quality of life. 4. Blood tests during fasting state to measure metabolic parameters. This is a prospective longitudinal observational study that lasts for 10 years.

Key facts

Study ID

NCT03413683

Run by

Chinese University of Hong Kong

People needed

100

Starts

2018-04-01

Expected to finish

2028-01-01

Last updated by the study team

2023-08-30

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• HIV infection with positive anti-HIV antibody
• Age ≥50 years

You may not qualify if…

• Refuses to consent

Where it is running

• Prince of Wales Hospital — Shatin, Hong Kong (enrolling)

Full record on ClinicalTrials.gov

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