Statins in Cerebral Blood Flow and Neuronal Activity--A Pilot Study

Completed

Conditions studied: Alzheimer's Disease

In brief

Specific Aim: Demonstrate that statins have an effect on cerebral blood flow and neuronal activity

Key facts

Study ID

NCT03411291

Run by

Cedars-Sinai Medical Center

People needed

18

Starts

2007-04-01

Expected to finish

2010-09-01

Last updated by the study team

2018-02-19

Who can join

Age: 45 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Otherwise healthy adults, male or female
• Age 45-65,
• Prior to treatment with any statin at a moderate or high dose -

You may not qualify if…

• Previous cerebral vascular accident,
• Traumatic brain injury,
• Subarachnoid hemorrhage,
• Vascular dementia,
• Alzheimer's Disease A
• Any other known vascular pathologies of the brain.
• Patients taking and/or receiving other known cerebrovascular enhancing medication/herbs and/or treatment (examples: tPA, gingko, triple H therapy, stenting procedures, etc.)
• Previous neurosurgery or intracranial procedures.
• Contraindication to MRI (pacemaker, neurostimulator, other surgical implants or metals which would contraindicate MRI).

Where it is running

• Cedars-Sinai Medical Center, S. Mark Taper Foundation Imaging Center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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