Mediterranean Style Diet and Low Glycemic Responses
Completed · Not applicable
Conditions studied: Insulin Sensitivity
In brief
the aim of this study is to evaluate whether a Mediterranean diet rich in pasta and other starchy foods with a (Low-GI), as compared with a similar Mediterranean diet containing very little pasta and based on starchy foods with a (Hi-GI) is able to reduce insulin and glucose concentrations during a prolonged test study meal.
Key facts
- Study ID
- NCT03410719
- Run by
- Purdue University
- People needed
- 166
- Starts
- 2018-01-04
- Expected to finish
- 2020-03-21
- Last updated by the study team
- 2020-07-17
Who can join
Age: 30 and older, up to 69. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- • BMI 25-37 kg/m2 with a waist circumference > 102 cm (males) or > 88 cm (females) and one additional feature of Metabolic Syndrome according to ATPIII [1], including blood pressure > 130/85 or treatment, fasting plasma glucose >100mg/dL, fasting triglycerides >150 mg/dL, HDL cholesterol < 40 mg/dL (males) or 50 mg/dL (females),
- weight stable (± 3 kg in previous 3 mo);
- no acute illness; and non-diabetic.
You may not qualify if…
- age <30 and >69years;
- fasting triglycerides ≥400 mg/dL;
- fasting cholesterol >240 mg/dL or low-density lipoprotein cholesterol>160 mg/dL
- fasting glucose >126 mg/dL,
- systolic blood pressure >160 mmHg, diastolic blood pressure >100 mmHg
- a BMI >37 kg/m2, weight changes during the previous 3 months (greater than ± 3 kg),
- stable intensive physical activity regimen during the previous 3 months (>3 h/wk of moderate or high intensity exercise, resistance or aerobic training).
- cardiovascular events (myocardial infarction or stroke) during the 6 months prior to the study;
- renal and liver failure (creatinine >1.7 mg/dl and ALT/AST >2 times than normal values, respectively);
- anaemia (Hb <12 g/dL);
- diabetes mellitus.
- If you are pregnant
Where it is running
- Purdue University — West Lafayette, Indiana, United States
Full record on ClinicalTrials.gov
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