A Study of the Feasibility of Prehospital Remote Ischemic Conditioning
Completed · Not applicable
Conditions studied: Chest Pain
In brief
Prospective, single center, single arm pilot study evaluating the feasibility of delivering remote ischemic conditioning (RIC) by emergency medical services (EMS) in the prehospital setting. Eligible patients will have chest pain or anginal equivalent symptoms and require ground ambulance transport to the hospital. All subjects will undergo the standard RIC procedure (i.e., up to four cycles of alternating 5-min inflation and 5-min deflation) with the autoRIC® device (CellAegis Devices, Inc., Toronto, Ontario). The primary objective is to evaluate the number of cycles of RIC completed in patients having the procedure initiated by EMS in the prehospital setting.
Key facts
- Study ID
- NCT03400579
- Run by
- University of North Carolina, Chapel Hill
- People needed
- 10
- Starts
- 2018-07-10
- Expected to finish
- 2019-10-01
- Last updated by the study team
- 2020-09-01
Who can join
Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Requiring 9-1-1 response to scene
- At least 18 years of age
- Experiencing non-traumatic chest pain or anginal equivalent symptom
- Not meeting EMS criteria for a suspected STEMI based on prehospital ECG
- Systolic blood pressure (SBP) between 100-180 mgm Hg
- Designated for ambulance transport to University of North Carolina Medical Center (Chapel Hill, NC)
- Capable of providing informed consent
You may not qualify if…
- Unconscious or otherwise in critical condition
- Lacking capacity to consent to the study
- Non-English speaking
- Pre-existing condition precluding blood pressure check or use of the autoRIC® at the discretion of the provider or listed here:
- Paresis of upper limb
- Pre-existing traumatic injury to arm
- Presence of an arteriovenous shunt for dialysis
- Prior mastectomy
- Existing peripheral inserted central catheter line
- Arm edema or other indication of upper extremity thrombosis
- Serial ECG evidence of evolving STEMI
Where it is running
- University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States
Full record on ClinicalTrials.gov
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