Mechanistic Clinical Trial of Advanced Imaging for CRT

Recruiting now · Not applicable

Conditions studied: Heart Failure, Systolic

In brief

This is a mechanistic clinical trial with randomization to guidance for the CRT procedure using cardiac magnetic resonance (CMR) and computed tomography angiography (CTA) versus a standard procedure.

Key facts

Study ID

NCT03398369

Run by

University of Virginia

People needed

180

Starts

2018-01-05

Expected to finish

2025-01-15

Last updated by the study team

2020-02-06

Who can join

Age: 20 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Chronic systolic HF
• LVEF 35% or less
• Guideline-based class I or II indication for CRT

You may not qualify if…

• Inability to provide informed consent
• Pregnancy
• Presence of metal embedded in the body due to prior accident or injury, as documented by skull films or other imaging
• Cerebral aneurysm clips
• Cochlear implants
• Other metallic implants known to be contraindications to CMR (does not include pacemakers and ICDs)
• Severe claustrophobia
• Acute kidney injury
• Acute renal failure or chronic kidney disease with GFR < 45 cc/min/1.73m2
• Liver transplant
• Gadolinium allergy
• >10% premature ventricular contraction (PVC) burden; and 13) estimated >10% atrial fibrillation (AF) burden based on available clinical data.

Where it is running

• University of Virginia Health System — Charlottesville, Virginia, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.