Twice Daily Versus Twice Weekly Soak-and-Seal Baths in Pediatric Atopic Dermatitis

Completed · Not applicable

Conditions studied: Atopic Dermatitis

In brief

There are few studies evaluating best bathing practices in the management of pediatric atopic dermatitis (AD). Trans-epidermal water loss plays a key role in the pathophysiology of AD. In concert with application of topical corticosteroids (TCS), we sought to investigate whether frequent soaking baths (i.e. twice daily for two weeks), followed immediately by application of an occlusive moisturizer (i.e. soak-and-seal), would be more effective than infrequent soaking baths (i.e. twice weekly for two weeks) in the management of AD.

Key facts

Study ID

NCT03397979

Run by

MaineHealth

People needed

63

Starts

2011-11-14

Expected to finish

2017-03-21

Last updated by the study team

2018-01-12

Who can join

Age: 1 and older, up to 11. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Infants and children ages 6 months to 11 years of age with moderate to severe atopic dermatitis according to the criteria of Hanifin and Rajka.

You may not qualify if…

• Patients with suspected or established primary immune deficiency, patients receiving systemic corticosteroids, ultraviolet light therapy, immuno-therapeutic agents, and/or anti-infective drugs less than 1 month from the onset of the study.

Where it is running

• Allergy and Asthma Associates of Maine — Portland, Maine, United States

Full record on ClinicalTrials.gov

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