Computerized Cognitive Intervention in the Oldest-Old
Completed · Not applicable
Conditions studied: Cognition, Dementia
In brief
Little is known about preventive strategies with immediate public health impact for cognitive functioning in the oldest-old (OO). Cognitive training improves cognitive functioning in the young-old (YO; 60 to 84), yet has not been examined in the OO. Clinical trials are needed to determine if computerized cognitive training is effective at preventing or delaying cognitive decline in the OO. In order to develop such trials, information regarding use of computers and internet by the OO, and the ability and interest in such a program, must be determined. This study will examine the effects of a computerized cognitive training program, CogniFit™, with a "classic" computerized games program, on cognitive functioning in cognitively healthy OO subjects. Information regarding use of computers and internet by the OO will be collected. Interest in and ability to complete a computerized cognitive training program will be examined, along with the cognitive, demographic, biological, and lifestyle characteristics related to this interest and ability. Efficacy of the CogniFit™ and games programs will be assessed immediately following the training and four months after completing the training. The researchers expect that those who use the CogniFit™ program will have greater improvements than those using the games program. Finally, the participants' characteristics related to the efficacy of the programs will be examined. Subjects recruited for this project will include those already participating in several studies of aging and cognition at the Mount Sinai School of Medicine. Recruiting from this pool of subjects will provide this program with baseline information regarding numerous subject characteristics, including cognition, family history, lifestyle, and cardiovascular information. This study will inform future large-scale clinical trials of computerized cognitive training programs in the elderly, as well as provide information regarding the efficacy of such training in the OO. In addition, the study will identify characteristics affecting efficacy of computerized training, and thus, may suggest mechanisms through which cognitive training improves cognitive functioning in the most senior citizens of our society.
Key facts
- Study ID
- NCT03397498
- Run by
- Icahn School of Medicine at Mount Sinai
- People needed
- 69
- Starts
- 2011-03-10
- Expected to finish
- 2014-12-16
- Last updated by the study team
- 2018-01-12
Who can join
Age: 80 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age 80+
- Normal cognition by consensus conference, MMSE> 25th percentile norm, CDR=0
- Has computer with internet access that is capable of running the computerized cognitive training program.
- Willing to dedicate the necessary time to the project
You may not qualify if…
- Prior or current participation in another cognitive intervention study
- Medical disease that precludes consistent participation or that affects cognition
- Poor vision
- Poor hearing
Where it is running
- Jewish Home Lifecare — New York, New York, United States
- Icahn School of Medicine at Mount Sinia — New York, New York, United States
Full record on ClinicalTrials.gov
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