Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma
Completed · Phase 3
Conditions studied: Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
In brief
The goal of this clinical study is to assess whether axicabtagene ciloleucel therapy improves the clinical outcome compared with standard of care second-line therapy in participants with relapsed/refractory diffuse large B-cell lymphoma (DLBCL).
Key facts
- Study ID
- NCT03391466
- Run by
- Kite, A Gilead Company
- People needed
- 359
- Starts
- 2018-01-25
- Expected to finish
- 2024-11-25
- Last updated by the study team
- 2025-12-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic Hospital — Phoenix, Arizona, United States
- UC San Diego Moores Cancer Center — La Jolla, California, United States
- UCLA — Santa Monica, California, United States
- Stanford Cancer Institute — Stanford, California, United States
- University of Miami Hospital and Clinics/Sylvester Comprehensive Cancer Center — Miami, Florida, United States
- Moffitt Cancer Center — Tampa, Florida, United States
- Northwestern University — Chicago, Illinois, United States
- University of Chicago Medical Center — Chicago, Illinois, United States
- University of Iowa Hospitals and Clinincs — Iowa City, Iowa, United States
- The University of Kansas Cancer Center — Kansas City, Kansas, United States
- University of Maryland, Greenbaum Comprehensive Cancer Center — Baltimore, Maryland, United States
- Dana-Farber Cancer Institute — Boston, Massachusetts, United States
- Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
- Mayo Clinic, Patient Location — Rochester, Minnesota, United States
- Washington University School of Medicine — St Louis, Missouri, United States
- John Theurer Cancer Center at Hackensack University Medical Center — Hackensack, New Jersey, United States
- Memorial Sloan Kettering Cancer Center — New York, New York, United States
- Icahn School of Medicine at Mount Sinai — New York, New York, United States
- University of Rochester Medical Center — Rochester, New York, United States
- Cleveland Clinic — Cleveland, Ohio, United States
- James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
- Thomas Jefferson University — Philadelphia, Pennsylvania, United States
- UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania, United States
- Sarah Cannon Research Institute — Nashville, Tennessee, United States
- Banner MD Anderson Cancer Center — Gilbert, Arizona, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.