Balloon Cryotherapy vs. Radiofrequency Ablation Pain Study
Completed
Conditions studied: Barrett Esophagus
In brief
Barrett's esophagus is a condition in which the normal lining of the lower esophagus is replaced with cells that predispose an individual to development of esophageal cancer. Treatment of Barrett's esophagus reduces the risk of progression to cancer. Treatment is provided endoscopically, via a variety of approved techniques including endoscopic mucosal resection, argon plasma coagulation, radiofrequency ablation (RFA), spray cryotherapy ablation and balloon cryotherapy ablation. A common side effect of ablation treatment is pain, thus making pain an important factor when discussing treatment options. It is speculated that balloon cryotherapy causes less pain than RFA but no head-to-head comparison trials exist to date. This multi-center, prospective cohort study aims to compare pre- and post-procedural pain for balloon cryotherapy versus RFA. Providing both patients and clinicians with data from a well-designed prospective study may help guide future physician/patient treatment discussions.
Key facts
- Study ID
- NCT03387982
- Run by
- Geisinger Clinic
- People needed
- 95
- Starts
- 2017-11-01
- Expected to finish
- 2021-02-16
- Last updated by the study team
- 2022-03-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with dysplastic Barrett's esophagus (LGD and HGD) naïve to ablation therapy presenting for ablation
- Age ≥ 18
- Ability to sign informed consent
You may not qualify if…
- Prior ablation treatment for Barrett's esophagus
- Pregnancy
Where it is running
- Long Island Jewish Medical Center — Queens, New York, United States
- Geisinger Medical Center — Danville, Pennsylvania, United States
- Medical University of South Carolina — Charleston, South Carolina, United States
- Virginia Commonwealth University — Richmond, Virginia, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.