Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
Completed · Phase 4
Conditions studied: Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture
In brief
The prevention of infection is the single most important goal influencing peri-operative care of patients with open fractures. Standard practice in the management of open fractures includes sterile technique and pre-operative skin preparation with an antiseptic solution. The available solutions kill bacteria and decrease the quantity of native skin flora, thereby decreasing surgical site infection (SSI). While there is extensive guidance on specific procedures for prophylactic antibiotic use and standards for sterile technique, the evidence regarding the choice of antiseptic skin preparation solution is very limited for open fracture surgery.
Key facts
- Study ID
- NCT03385304
- Run by
- University of Maryland, Baltimore
- People needed
- 1638
- Starts
- 2018-04-08
- Expected to finish
- 2022-06-27
- Last updated by the study team
- 2023-03-31
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- The CORE Institute / Banner University Medical Center — Phoenix, Arizona, United States
- Banner - University Medical Center Tucson — Tucson, Arizona, United States
- University of California San Francisco — San Francisco, California, United States
- University of Florida — Gainesville, Florida, United States
- Indiana University Health Methodist Hospital — Indianapolis, Indiana, United States
- University of Maryland, R Adams Cowley Shock Trauma Center — Baltimore, Maryland, United States
- Wright State University / Miami Valley Hospital — Dayton, Ohio, United States
- Greenville Health System — Greenville, South Carolina, United States
- Vanderbilt University — Nashville, Tennessee, United States
- San Antonio Military Medical Center — Fort Sam Houston, Texas, United States
- McGovern Medical School at University of Texas Health Science Center Houston — Houston, Texas, United States
- Hamilton Health Sciences — Hamilton, Ontario, Canada
- McMaster University, Center for Evidence-Based Orthopaedics — Hamilton, Ontario, Canada
- Hospital Parc Tauli de Sabadell — Barcelona, Spain
- Vall d'Hebron University Hospital — Barcelona, Spain
Full record on ClinicalTrials.gov
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