PRISM-GENOMICS-Smoking Cessation for Patients With Coronary Artery Disease Undergoing Cardiac Catheterization or Having a Heart Attack at Barnes Hospital in St. Louis Mo
Status unconfirmed · Not applicable
Conditions studied: Coronary Artery Disease, Smoking Cessation
In brief
It has previously been shown that patients with coronary artery disease may have a harder time quitting smoking if they have a specific genetic profile and that these individuals have a better chance at quitting if they receive nicotine replacement therapy. The investigators hypothesize that determining which individuals with coronary artery disease should receive nicotine replacement therapy based on their genotype may improve the number of individuals who are able to quit smoking.This study randomizes treatment to that determined by the patient's genotype compared to standard, non-genotype-guided, treatment.
Key facts
- Study ID
- NCT03383224
- Run by
- Washington University School of Medicine
- People needed
- 100
- Starts
- 2015-07-21
- Expected to finish
- 2025-07-21
- Last updated by the study team
- 2021-11-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult
- presenting to Barnes hospital cardiac catheterization laboratory with coronary artery disease or admitted to Barnes hospital within 24 hours of a type 1 myocardial infarction (heart attack)
- active smoker at time of presentation to Barnes Hospital
- participating in PRISM-GENOMICS observational study
You may not qualify if…
- Unable to provide informed consent
- Unable to answer questions (e.g. intubated)
- Incarcerated
- Complications of myocardial infarction (such as shock, hemodynamic instability, life- threatening infection, etc)
- Women of child-bearing age with positive pregnancy test or who is breast feeding
Where it is running
- Barnes Hospital — St Louis, Missouri, United States
Full record on ClinicalTrials.gov
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