Diffusion Tensor Imaging in Predicting Development of Chemotherapy Induced Peripheral Neuropathy in Patients With Breast Cancer (CIPN)
Completed · Not applicable
Conditions studied: Breast Carcinoma, Breast Cancer, Neuropathy;Peripheral, Neuropathy
In brief
This pilot early phase I trial studies how well diffusion tensor imaging works in predicting development of chemotherapy induced peripheral neuropathy in patients with breast cancer. Diffusion tensor imaging may help to get better pictures of the nerves of feet and lower legs before and after chemotherapy treatment and may help to predict the risk of developing peripheral neuropathy.
Key facts
- Study ID
- NCT03365895
- Run by
- University of Arizona
- People needed
- 17
- Starts
- 2017-08-11
- Expected to finish
- 2020-10-02
- Last updated by the study team
- 2020-11-19
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Be capable of understanding the investigational nature of the study and all pertinent aspects of the study
- Be capable of signing and providing written consent in accordance with institutional and federal guidelines
- Have a histologically-confirmed diagnosis of breast cancer
- Need to be treated with taxane containing chemotherapy as determined by their treating physician
- Be able to undergo magnetic resonance (MR) imaging
- Be willing and able to comply with scheduled visits, treatment plan, and MR imaging
You may not qualify if…
- Have non-MRI compatible metallic objects on/in body
- Have metallic hardware in the lower extremity which is MR compatible however would create too much artifact for MR examination
- Are unable to lay still in the MR scanner for length of examination
- Have severe claustrophobia
- Have pre-existing peripheral neuropathy from other medical conditions or due to cancer
- Have diagnosis of diabetes
- Pregnant patients
- Prior exposure to neurotoxic chemotherapy
Where it is running
- The University of Arizona Cancer Center — Tucson, Arizona, United States
Full record on ClinicalTrials.gov
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