Comparison of Triazolam and Midazolam for Anxiolysis During Dental Treatment in the Pediatric Patient

Completed · Not applicable

Conditions studied: Dental Anxiety

In brief

This study will evaluate the perceptions of the effects of two anxiolytic medications commonly used during dental treatment in patients weighing 40 kilograms or more.

Key facts

Study ID: NCT03360123
Run by: University of Pittsburgh
People needed: 4
Starts: 2018-01-26
Expected to finish: 2018-04-11
Last updated by the study team: 2018-06-19

Who can join

Age: 7 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Weigh 40 kilograms or more.
2/4 or 3/4 Frankl Behavioral Rating at their evaluation appointment.
Dental treatment that requires two sedation appointments. Dental treatment that requires sedation includes: fillings, crowns, pulpotomies and/or extractions.
Between the ages of 7-17 years old.

You may not qualify if…

Patients taking any of the following medications will be excluded from the study: Atripia, cimetidine, diltiazem, erythromycin, fluconazole, grapefruit juice, isoniazid, itraconazole, ketoconazole, nefazodone, rifampicin, ritonavir, fusidic acid, idelalisisb, methadone, olanzapine, thalidomide and/or troleandomycin.
Pregnant patients will be excluded.
Patients that have HIV-1 that is being treated with a protease inhibitor will be excluded.
Patients with a MTHFR mutation will be excluded.
Patients with acute narrow angle glaucoma will be excluded.
Patients that have had a previous adverse, paradoxical or allergic reaction to any benzodiazepines will be excluded from the study.
Patients unable to swallow medication in tablet form.
Patients that do not speak English as their primary language.

Where it is running

Children's Hospital of Pittsburgh of UPMC — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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